We want to answer your questions and support you on your weight-loss journey. Visit our Medication Guide for more information about CONTRAVE, or call one of our customer service representatives at 1-800-905-5576. You’ll also find answers to the most commonly asked questions below
CONTRAVE® (naltrexone HCI/bupropion HCl) is a prescription weight-loss medicine that may help adults with obesity (BMI greater than or equal to 30 kg/m2), or who are overweight (BMI greater than or equal to 27 kg/m2) with at least one weight-related medical condition, lose weight and keep the weight off. CONTRAVE should be used along with diet and exercise.
CONTRAVE contains 2 well-known FDA-approved drugs, naltrexone and bupropion, which have each been on the market for the treatment of other conditions for over 30 years. However, the individual medicines in CONTRAVE are not approved for weight loss when used on their own, and CONTRAVE is not indicated for the treatment of depression, smoking cessation, or alcohol or opioid dependence.
The exact neurochemical effects of CONTRAVE leading to weight loss are not fully understood.
CONTRAVE is believed to work on two areas of the brain—the hypothalamus (your hunger center) to help reduce hunger and the mesolimbic reward system to help control cravings—that can get in the way of weight loss.
CONTRAVE is approved for use in adults with a body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight) who have at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol. It is to be used along with a reduced-calorie diet and increased physical activity.
CONTRAVE is not for everyone. Do not take CONTRAVE if you:
See the Medication Guide to learn more.
Take CONTRAVE exactly as your doctor tells you to.
CONTRAVE dosing should be increased slowly according to the following schedule:
Standard Dosage for Patients Taking CONTRAVE
Pills are featured for illustrative purposes, not shown to actual size.
It’s important to take CONTRAVE exactly as your doctor prescribes it. Keep in mind that some people, like those with renal or hepatic impairment, or those taking certain other medications, may need to follow a different dosing schedule. A total daily dosage of 4 CONTRAVE pills (i.e., 2 pills taken twice per day) should be reached at the start of week 4.
Your healthcare provider should tell you to stop taking CONTRAVE if you have not lost a certain amount of weight after 16 weeks of treatment.
To learn more about dosing, see the Medication Guide.
The most common side effects reported with CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping (insomnia), dry mouth, and diarrhea.
In general, it is recommended you drink plenty of water when taking CONTRAVE. If you experience nausea, you may also want to eat a small amount of dry toast with CONTRAVE. If symptoms do not improve, please consult with your doctor who may also recommend an over-the-counter anti-nausea medication for you.
If you experience any of the following, stop taking CONTRAVE and tell your doctor right away:
See the Full Prescribing Information or the Medication Guide to learn more about the possible side effects of CONTRAVE.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Bella Pharmacy (UpScript): 1-855-288-8428 -or- upscripthealth.com
Ridgeway Mail Order Pharmacy: 1-800-630-3214 -or- ridgeway.pharmacy/HomeDelivery
Lombard Pharmacy: 1-844-232-9920 -or- lombardpharmacy.com/contrave
We no longer feature the login and account sections on the CONTRAVE.com website. To help simplify your CONTRAVE experience, we now allow users to sign up for the Savings Coupon Card without a password. If you have questions about your account, please call 1-800-905-5576.
Once you sign up for the CONTRAVE Savings Coupon Card, you will be able to download it right away online. Print it or take a picture of it on your smartphone and bring it with you the first time you fill your prescription. Once you use your Savings Coupon Card at the pharmacy, you do not need to bring it again. The pharmacy will keep your card information on file.
If your insurance covers CONTRAVE, you may pay as low as $20* with the Savings Coupon Card. If you don’t have insurance or if your insurance doesn’t cover CONTRAVE, you will pay no more than $199*.
*To learn more about eligibility, visit the Savings Terms and Conditions page.
To get CONTRAVE at a guaranteed low price, you can use the CurAccess Program. You will pay $99 or Less + FREE Shipping for your CONTRAVE prescription. Depending on your insurance coverage, you may even pay less.
Learn More about the CurAccess Program here.
You can sign up for the CONTRAVE Savings Coupon Card here. If you are having trouble signing up online, you can call 1-800-905-5576 for assistance.
You are not eligible if your prescriptions are paid by any state or other federally funded programs, including, but not limited to, Medicare or Medicaid, Medigap, VA or DOD, or TRICARE, or where prohibited by law.
Additionally, the CONTRAVE Savings Coupon Card cannot be used if you are purchasing your prescription through the Get CONTRAVE Now online consult or the CurAccess Program. However, Medicare Part D and TRICARE beneficiaries could receive the CONTRAVE Savings Coupon Card benefits if your prescription will be processed with the assumption that you are a cash-paying customer.
To learn more about eligibility, visit the Savings Terms and Conditions page.
You will get a similar discount whether you pick up your prescription at the pharmacy, or receive it through the mail from your pharmacy. You could also obtain CONTRAVE through the CurAccess Program. With the CurAccess Program, You will pay $99 or Less + FREE Shipping to all 50 states.
Learn More about the CurAccess Program here.
You don’t need a replacement card if your pharmacy already has your information on file. Call your pharmacy to check. If they don’t have your information, then call 1-800-905-5576 for assistance.
If you still have your card on hand, you can give your new pharmacy the same card ID number. If you’ve lost the card, call a 1-800-905-5576 for assistance. If you’re switching to another pharmacy within the same chain, your information should still be in the system.
Contact your local pharmacist and ask them to run your insurance to check your coverage for CONTRAVE, or, contact Ridgeway Pharmacy or call 1.800.630.3214 they can help determine your best option.
If your insurance covers CONTRAVE, you may pay as low as $20* with the Savings Coupon Card. If you don’t have insurance or if your insurance doesn’t cover CONTRAVE, you will pay no more than $199*.
*To learn more about eligibility, visit the Savings Terms and Conditions page.
If you have private health insurance that covers CONTRAVE, pricing may vary. Ask your local pharmacist to run your insurance to check your coverage for CONTRAVE.
To get CONTRAVE at a guaranteed low price, you can use the CurAccess Program. The CurAccess Program helps patients SAVE on CONTRAVE. With the CurAccess Program, You will pay $99 or Less + FREE Shipping. You may pay even less depending on your insurance coverage. Contact Ridgeway Pharmacy or call 1.800.630.3214 so they can help determine your best option.
Use the CurAccess Program to SAVE on CONTRAVE. You will pay $99 or less + FREE Shipping on your CONTRAVE prescription and receive FREE shipping through the program. Depending on your insurance coverage, you may even pay less. CurAccess’s partner pharmacy, Ridgeway, will help you determine your best option.
The steps to use the CurAccess Program are as follows:
Currax Pharmaceuticals LLC, the company that brings you CONTRAVE, respects your right to have personal and medical information kept confidential. Only Currax Pharmaceuticals LLC and its third-party partners will use your information.
Currax Pharmaceuticals LLC and companies providing services to Currax Pharmaceuticals LLC will not sell or rent your personally identifiable information, as described in our Privacy Policy.
Setting up an online consultation is simple. First, click the “TALK TO A DOCTOR ONLINE” button. You will be directed to a consult site offered by one of our partners where you can set up an account and your medical profile. Your profile will be reviewed, and you will be notified if you are a good potential candidate for a CONTRAVE prescription. Depending on what state you reside in, you will then be asked to participate in a video or telephone consultation with a doctor. Only a doctor can determine if CONTRAVE is right for you.
The Get CONTRAVE Now online service and participating healthcare professionals are independent and not employees or contractors of Currax Pharmaceuticals LLC.
The CONTRAVE Savings Card cannot be used for prescriptions filled through the online doctor consult option.
The $45 consult fee is a one-time payment for your online doctor visit, which is similar to the standard fee (or co-pay) you would incur for an in-person doctor visit. You should check with your insurance provider to determine if the consult fee can be reimbursed by your specific plan. Choosing the online consultation may make the process of getting started on CONTRAVE easier or more convenient. It is possible your doctor may request follow-up consults for an additional fee.
Patients who use the Get CONTRAVE Now service will receive a discount from the retail pharmacy price, without having to use the CONTRAVE Savings Coupon Card. Your CONTRAVE prescription will cost less than $99 per month with FREE standard shipping. Our Get CONTRAVE Now partners may also check if you have insurance coverage, which may also lower the cost of your prescription.
You are not eligible if prescriptions are paid by any state or federally funded programs, including, but not limited to Medicare or Medicaid, Medigap, VA or DOD, or TRICARE, or where prohibited by law.
The CONTRAVE Savings Card cannot be used for prescriptions filled through Get CONTRAVE Now.
Local pharmacy pickup is not available at this time.
The CurAccess Program helps patients SAVE on CONTRAVE. You will pay $99 or Less + FREE Shipping for your CONTRAVE prescription through the program. Depending on your insurance coverage, you may even pay less.
The steps to use the CurAccess Program are as follows:
Yes, we offer both through our CurAccess Program. With our CurAccess Program, you will pay $99 or Less + FREE Shipping. Depending on your insurance, you may pay even less.
If you already have a CONTRAVE prescription or wish to transfer it from your local pharmacy, Ridgeway Mail Order Pharmacy will transfer it for you.
If you participated in the Get CONTRAVE Now online consultation service, FREE shipping would have been set up directly for you, with no further action needed.
The CONTRAVE Savings Card cannot be used for prescriptions filled through Get CONTRAVE Now or our CurAccess Program.
The CONTRAVE Savings Coupon Card cannot be combined with offers from our telemedicine partners or with our CurAccess Program.
The CurAccess Program can only be used to fill prescriptions for Currax products, such as CONTRAVE. Please contact Ridgeway Mail Order Pharmacy by calling 1-800-630-3214. Please note: Your CONTRAVE prescription is delivered via standard USPS first-class shipping; any other prescriptions may be subject to insurance costs, shipping rates, and additional fees.
Yes. With our CurAccess Program, you will pay $99 or Less + FREE Shipping. Depending on your insurance, you may pay even less.
To get started:
CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.
CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.
CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.
CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.
CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.
While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when you start taking CONTRAVE or when your dose changes.
Stop taking CONTRAVE and call a healthcare provider right away if you or your family members notice any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempts to commit suicide; depression; anxiety; feeling agitated or restless; panic attacks; irritability; aggression, anger, or violence; acting on dangerous impulses; an extreme increase in activity and talking; other unusual changes in behavior or mood; trouble sleeping.
CONTRAVE is not approved for use in children under the age of 18.
Do not take CONTRAVE if you have uncontrolled high blood pressure; have or have had seizures; use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN; have or have had an eating disorder called anorexia or bulimia; are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal; drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti‐seizure medicines and stop using them all of a sudden; are taking or have taken medicines called monoamine oxidase inhibitors (MAOIs) in the past 14 days; or are allergic to any of the ingredients in CONTRAVE.
Tell your healthcare provider about all of your medical conditions including if you have: depression or other mental illnesses; attempted suicide; seizures; head injury; tumor or infection of brain or spine; low blood sugar or low sodium; liver or kidney problems; high blood pressure; heart attack, heart problems, or stroke; eating disorder; drinking a lot of alcohol; prescription medicine or street drug abuse; are 65 or older; diabetes; pregnant or planning to become pregnant; or breastfeeding.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Get emergency medical help right away if you take opioids and you:
The most common side effects of CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping, dry mouth, and diarrhea. These are not all of the possible side effects of CONTRAVE.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.
CONTRAVE should be used with a reduced-calorie diet and increased physical activity.
It is not known if CONTRAVE changes your risk of heart problems or stroke or of death due to heart problems or stroke.
It is not known if CONTRAVE is safe and effective when taken with other prescription, over-the-counter, or herbal weight-loss products.
CONTRAVE is not approved to treat depression or other mental illnesses, or to help people quit smoking (smoking cessation).
Please see Full Prescribing Information, including Medication Guide, for CONTRAVE.