What to Know About CONTRAVE, Our Telemedicine Service, and Savings Programs.

We want to answer your questions and support you on your weight-loss journey. Visit our Medication Guide for more information about CONTRAVE, or call one of our customer service representatives at 1-800-905-5576. You’ll also find answers to the most commonly asked questions below

Learn About CONTRAVE

CONTRAVE® (naltrexone HCI/bupropion HCl) is a prescription weight-loss medicine that may help adults with obesity (BMI greater than or equal to 30 kg/m2), or who are overweight (BMI greater than or equal to 27 kg/m2) with at least one weight-related medical condition, lose weight and keep the weight off. CONTRAVE should be used along with diet and exercise.

CONTRAVE contains 2 well-known FDA-approved drugs, naltrexone and bupropion, which have each been on the market for the treatment of other conditions for over 30 years. However, the individual medicines in CONTRAVE are not approved for weight loss when used on their own, and CONTRAVE is not indicated for the treatment of depression, smoking cessation, or alcohol or opioid dependence.

The exact neurochemical effects of CONTRAVE leading to weight loss are not fully understood.

 

CONTRAVE is believed to work on two areas of the brain—the hypothalamus (your hunger center) to help reduce hunger and the mesolimbic reward system to help control cravings—that can get in the way of weight loss.

CONTRAVE is approved for use in adults with a body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight) who have at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol. It is to be used along with a reduced-calorie diet and increased physical activity.

 

CONTRAVE is not for everyone. Do not take CONTRAVE if you:

  • have uncontrolled hypertension
  • have or have had seizures.
  • use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN
  • have or have had an eating disorder called anorexia (eating very little) or bulimia (eating too much and vomiting to avoid gaining weight)
  • are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal
  • drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti-seizure medicines and you stop using them all of a sudden
  • are taking medicines called monoamine oxidase inhibitors (MAOIs). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including linezolid. Do not start CONTRAVE until you have stopped taking your MAOI for at least 14 days
  • are allergic to naltrexone or bupropion or any of the ingredients in CONTRAVE. See the Medication Guide for a complete list of ingredients in CONTRAVE

See the Medication Guide to learn more.

Take CONTRAVE exactly as your doctor tells you to.

 

CONTRAVE dosing should be increased slowly according to the following schedule:

 

Standard Dosage for Patients Taking CONTRAVE

Pills are featured for illustrative purposes, not shown to actual size.

 

It’s important to take CONTRAVE exactly as your doctor prescribes it. Keep in mind that some people, like those with renal or hepatic impairment, or those taking certain other medications, may need to follow a different dosing schedule. A total daily dosage of 4 CONTRAVE pills (i.e., 2 pills taken twice per day) should be reached at the start of week 4.

 

Your healthcare provider should tell you to stop taking CONTRAVE if you have not lost a certain amount of weight after 16 weeks of treatment.

  • Do not take more than 2 pills at the same time or more than 4 pills in 1 day
  • Do not take CONTRAVE with high-fat meals. It may increase your risk of seizures

 

To learn more about dosing, see the Medication Guide.

The most common side effects reported with CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping (insomnia), dry mouth, and diarrhea.

If you experience any of the following, stop taking CONTRAVE and tell your doctor right away:

  • Suicidal thoughts or actions
  • Seizures (you should not take CONTRAVE again if you have a seizure).
  • Risk of opioid overdose (One of the ingredients in CONTRAVE [naltrexone] can increase your chance of having an opioid overdose if you take opioid medicines while taking CONTRAVE)
  • Sudden opioid withdrawal (people who take CONTRAVE must not use any type of opioid for at least 7-10 days before starting CONTRAVE)
  • Severe allergic reaction (signs and symptoms include rash, itching, hives, fever, swollen lymph glands, painful sores in your mouth or around your eyes, swelling of your lips or tongue, chest pain, or trouble breathing)
  • Increases in blood pressure or heart rate
  • Liver damage or hepatitis (symptoms include stomach area pain lasting more than a few days, dark urine, yellowing of the whites of your eyes, or tiredness)
  • Manic episodes
  • Visual problems (symptoms of angle-closure glaucoma include eye pain, changes in vision, swelling, or redness in or around the eye)
  • Low blood sugar (hypoglycemia) in people with type 2 diabetes mellitus who also take medicines to treat their diabetes (such as insulin or sulfonylureas)

See the Full Prescribing Information or the Medication Guide to learn more about the possible side effects of CONTRAVE.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Need Help Refilling a CONTRAVE Prescription?

    1. Look at your CONTRAVE prescription bottle. Do you see a pharmacy name and phone number on the bottle? That’s your pharmacy.
    2. Did you get your CONTRAVE prescription from a local pharmacy? If yes, you should contact them directly. If you are interested in transferring your prescription to a Direct Home Delivery pharmacy, click here.

 

  1. If you used the Get CONTRAVE Now® doctor consult, your prescription would have been fulfilled by Bella Pharmacy in Sandy, Utah (UpScript), Ridgeway, or Lombard. Please contact the respective pharmacy to refill your prescription.

Bella Pharmacy (UpScript): 1-855-288-8428
Ridgeway Mail Order Pharmacy: 1-800-630-3214
Lombard Pharmacy: 1-844-232-9920

About the CONTRAVE Savings Coupon Card & Insurance Coverage for CONTRAVE

We no longer feature the login and account sections on the CONTRAVE.com website. To help simplify your CONTRAVE experience, we now allow users to sign up for the Savings Coupon Card without a password. If you have questions about your account, please reach out to our customer service representatives at 1-800-905-5576 and they will be happy to assist you.

Once you sign up for the CONTRAVE Savings Coupon Card, you will be able to download it right away online. Print it or take a picture of it on your smartphone and bring it with you the first time you fill your prescription. Once you use your Savings Coupon Card at the pharmacy, you do not need to bring it again. The pharmacy will keep your card information on file.

If you’re paying cash, or if you have insurance that does not cover CONTRAVE, you may pay less than $4 a day for your monthly prescription. If you have private health insurance that covers CONTRAVE, you may pay less than $2 a day. Tell your pharmacist what kind of health insurance you have so you can pay the lowest copay possible.

You can sign up for the CONTRAVE Savings Coupon Card here. If you are having trouble signing up online, you can call 1-800-905-5576 for assistance.

You are not eligible if your prescriptions are paid by any state or other federally funded programs, including, but not limited to, Medicare or Medicaid, Medigap, VA or DOD, or TRICARE, or where prohibited by law.

 

Additionally, the CONTRAVE Savings Coupon Card cannot be used if you are purchasing your prescription through the Get CONTRAVE Now online consult or Special Direct Pricing.

 

To learn more about eligibility, visit the Savings Terms and Conditions page.

Yes, you will get a similar discount whether you pick up your prescription at the pharmacy or receive it through the mail. You will receive a similar discount whether your mailed prescription is for one month or three months.

You don’t need a replacement card if your pharmacy already has your information on file. Call your pharmacy to check. If they don’t have your information, then call 1-800-905-5576 for assistance.

If you still have your card on hand, you can give your new pharmacy the same card ID number. If you’ve lost the card, call a customer service representative at 1-800-905-5576 for assistance. If you’re switching to another pharmacy within the same chain, your information should still be in the system.

Contact your local pharmacist and ask them to run your insurance to check your coverage for CONTRAVE.

If your prescription insurance covers CONTRAVE, you may pay less than $2 per day for your monthly prescription using the CONTRAVE Savings Coupon Card. If your prescription insurance does not cover CONTRAVE, or if you pay cash, you may pay less than $4 per day for your monthly prescription using the CONTRAVE Savings Coupon Card. If you are unsure, contact your pharmacy and ask them to run your insurance for a sample 30-day CONTRAVE prescription to determine your monthly cost.

 

As a reminder, you can also get CONTRAVE through the Special Direct Pricing program and pay $99/month (approximately $3 a day) for your CONTRAVE prescription. You can transfer your existing prescription to the Special Direct Pricing program. Orr if you do not already have a prescription, ask your doctor if CONTRAVE is right for you or talk to a doctor online through the Get CONTRAVE Now program. For patients whose insurance plan does not cover CONTRAVE, Special Direct Pricing is the lowest-cost way to get CONTRAVE. No coupon needed, quick and easy delivery directly to your doorstep.

 

All CONTRAVE discount programs are subject to eligibility.

You can sign up for our CONTRAVE Savings Coupon Card, to pay less than $4 per day for your prescription, or you may try Special Direct Pricing and pay $99/month (approximately $3 per day). You may also ask your company to offer insurance plans that cover weight-loss medications. For patients whose insurance plan does not cover CONTRAVE, Special Direct Pricing is the lowest cost way to get CONTRAVE. No coupon needed and offers standard shipping with quick and easy delivery directly to your doorstep. You can also send a letter to your employer requesting that they offer prescription drug coverage for weight-loss medications. This will not help you immediately, but it may influence your employer to cover weight-loss medications in the future.

Currax Pharmaceuticals LLC, the company that brings you CONTRAVE, respects your right to have personal and medical information kept confidential. Only Currax Pharmaceuticals LLC and its third-party partners will use your information.

 

Currax Pharmaceuticals LLC and companies providing services to Currax Pharmaceuticals LLC will not sell or rent your personally identifiable information, as described in our Privacy Policy.

About the Online Doctor Consult

Setting up an online consultation is simple. First, click the “TALK TO A DOCTOR ONLINE” button. You will be directed to a consult site offered by one of our partners where you can set up an account and your medical profile. Your profile will be reviewed, and you will be notified if you are a good potential candidate for a CONTRAVE prescription. You will then be asked to participate in a video or telephone consultation with a doctor. Only a doctor can determine if CONTRAVE is right for you.

 

The Get CONTRAVE Now online service and participating healthcare professionals are independent and not employees or contractors of Currax Pharmaceuticals LLC.

 

The CONTRAVE Savings Coupon Card cannot be used for prescriptions filled through online doctor consult.

This consult fee is a payment for your online doctor visit, which is similar to the standard fee (or co-pay) you would incur for an in-person doctor visit. You should check with your insurance provider to determine if the consult fee can be reimbursed by your specific plan. Choosing the online consultation may make the process of getting started on CONTRAVE more convenient.

Patients who use the Get CONTRAVE Now service will receive a discount from the retail pharmacy price, even without using the CONTRAVE Savings Coupon Card. Your CONTRAVE prescription will cost no more than $99 per month (approximately $3 per day). Our Get CONTRAVE Now partners may also check if you have insurance coverage, which may also lower the cost of your prescription.

 

You are not eligible if prescriptions are paid by any state or federally funded programs, including, but not limited to Medicare or Medicaid, Medigap, VA or DOD, or TRICARE, or where prohibited by law.

 

The CONTRAVE Savings Coupon Card cannot be used for prescriptions filled through Get CONTRAVE Now.

About Special Direct Pricing

Once you sign up, Ridgeway Mail Order Pharmacy will deliver your CONTRAVE prescription straight to your door with standard shipping. If you already have a CONTRAVE prescription or wish to transfer it from your local pharmacy, Ridgeway Mail Order Pharmacy will transfer it for you. You can create an account here or call 1-800-630-3214 to sign up for home delivery.

 

If you participated in the Get CONTRAVE Now online consultation service, Special Direct Pricing will be set up directly for you, with no further action needed.

 

The CONTRAVE Savings Coupon Card cannot be used for prescriptions filled through Get CONTRAVE Now or Special Direct Pricing.

 

Get CONTRAVE Now and Special Direct Pricing programs are offered by our partners.

Currently, the CONTRAVE Savings Coupon Card cannot be used with the online consultation or Special Direct Pricing option. But your monthly CONTRAVE prescription should cost just about the same amount whether you use the online consultation and home delivery service or use your CONTRAVE Savings Coupon Card at a local pharmacy.

No. Ridgeway Mail Order Pharmacy will only be able to fill prescriptions for Currax products, such as CONTRAVE. Once you have signed up for the home-delivery service, please contact Ridgeway Mail Order Pharmacy by calling 1-800-630-3214. Please note: Your CONTRAVE prescription will be delivered via standard USPS first-class shipping; any other prescriptions may be subject to additional insurance costs, shipping rates, and fees.

Yes. Call our Special Direct Pricing service partner, Ridgeway Mail Order Pharmacy at 1-800-630-3214. They will create your account and complete the prescription transfer for you. Please note: If you have insurance that may cover CONTRAVE, you could pay less than $99. Ridgeway Mail Order Pharmacy can help you determine your final price.

 

If you used the Get CONTRAVE Now online consultation service, enrollment instructions for Special Direct Pricing will be provided after the telemedicine consultation.

To get started, call our home delivery partner Ridgeway Mail Order Pharmacy, at 1-800-630-3214. After setting up your account, they will connect with your doctor so that you can have your CONTRAVE prescription delivered to your home.

IMPORTANT SAFETY INFORMATION
What is CONTRAVE?
See More

CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.

CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.

IMPORTANT SAFETY INFORMATION
See More

CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.

What is CONTRAVE?
See More

CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.

IMPORTANT SAFETY INFORMATION
What is CONTRAVE?
See Less

CONTRAVE can cause serious side effects including:
Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment.

While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when you start taking CONTRAVE or when your dose changes.

Stop taking CONTRAVE and call a healthcare provider right away if you or your family members notice any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempts to commit suicide; depression; anxiety; feeling agitated or restless; panic attacks; irritability; aggression, anger, or violence; acting on dangerous impulses; an extreme increase in activity and talking; other unusual changes in behavior or mood; trouble sleeping.

CONTRAVE is not approved for use in children under the age of 18.

Do not take CONTRAVE if you have uncontrolled high blood pressure; have or have had seizures; use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN; have or have had an eating disorder called anorexia or bulimia; are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal; drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti‐seizure medicines and stop using them all of a sudden; are taking or have taken medicines called monoamine oxidase inhibitors (MAOIs) in the past 14 days; or are allergic to any of the ingredients in CONTRAVE.

Tell your healthcare provider about all of your medical conditions including if you have: depression or other mental illnesses; attempted suicide; seizures; head injury; tumor or infection of brain or spine; low blood sugar or low sodium; liver or kidney problems; high blood pressure; heart attack, heart problems, or stroke; eating disorder; drinking a lot of alcohol; prescription medicine or street drug abuse; are 65 or older; diabetes; pregnant or planning to become pregnant; or breastfeeding.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

CONTRAVE may cause serious side effects, including:
  • Seizures. There is a risk of having a seizure when you take CONTRAVE. The risk of seizure is higher in people who take higher doses of CONTRAVE, have certain medical conditions, or take CONTRAVE with certain other medicines. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. If you have a seizure while taking CONTRAVE, stop taking CONTRAVE and call your healthcare provider right away.
  • Risk of opioid overdose. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone. This can lead to serious injury, coma, or death.

    Get emergency medical help right away if you take opioids and you:

    • have trouble breathing
    • become very drowsy with slowed breathing
    • have slow, shallow breathing
    • feel faint, very dizzy, confused, or have unusual symptoms
  • Sudden opioid withdrawal. People who take CONTRAVE must not use any type of opioid including street drugs, prescription pain medicines, cough, cold, or diarrhea medicines that contain opioids, or opioid dependence treatments, for at least 7 to 10 days before starting CONTRAVE. Using opioids in the 7 to 10 days before you start taking CONTRAVE may cause you to suddenly have symptoms of opioid withdrawal when you take it. Sudden opioid withdrawal can be severe, and you may need to go to the hospital. Tell your healthcare provider you are taking CONTRAVE before a medical procedure or surgery.
  • Severe allergic reactions. Stop taking CONTRAVE and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of an allergic reaction: rash, itching, hives, fever, swollen lymph glands, painful sores in your mouth or around your eyes, swelling of your lips or tongue, chest pain, or trouble breathing.
  • Increases in blood pressure or heart rate. Some people may get high blood pressure or have a higher heart rate when taking CONTRAVE. Your healthcare provider should check your blood pressure and heart rate before you start taking, and while you take CONTRAVE.
  • Liver damage or hepatitis. Stop taking CONTRAVE and tell your healthcare provider if you have any of the following symptoms of liver problems: stomach area pain lasting more than a few days, dark urine, yellowing of the whites of your eyes, or tiredness. Your healthcare provider may need to stop treating you with CONTRAVE if you get signs or symptoms of a serious liver problem.
  • Manic episodes. Bupropion can cause some people who were manic or depressed in the past to become manic or depressed again.
  • Visual problems (angle-closure glaucoma). Signs and symptoms may include: eye pain, changes in vision, swelling or redness in or around the eye. Talk with your healthcare provider to find out if you are at risk for angle‐closure glaucoma and to get treatment to prevent it if you are at risk.
  • Increased risk of low blood sugar in people with type 2 diabetes mellitus who also take medicines to treat their diabetes (such as insulin or sulfonylureas). You should check your blood sugar before you start taking CONTRAVE and while you take CONTRAVE.

The most common side effects of CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping, dry mouth, and diarrhea. These are not all of the possible side effects of CONTRAVE.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

What is CONTRAVE?

CONTRAVE is a prescription weight-loss medicine that may help some adults with a body mass index (BMI) of 30 kg/m2 or greater (obese), or adults with a BMI of 27 kg/m2 or greater (overweight) with at least one weight-related medical problem such as high blood pressure, high cholesterol, or type 2 diabetes, lose weight and keep the weight off.

CONTRAVE should be used with a reduced-calorie diet and increased physical activity.

It is not known if CONTRAVE changes your risk of heart problems or stroke or of death due to heart problems or stroke.

It is not known if CONTRAVE is safe and effective when taken with other prescription, over-the-counter, or herbal weight-loss products.

CONTRAVE is not approved to treat depression or other mental illnesses, or to help people quit smoking (smoking cessation).

Please see Full Prescribing Information, including Medication Guide, for CONTRAVE.